Actiflash是一種小的類固醇配體,在光誘導(dǎo)下激活工程蛋白。它可用于在活細(xì)胞培養(yǎng)物和動(dòng)物中精確控制蛋白質(zhì)活性至單細(xì)胞水平。
How does it work?Actiflash is a tamoxifen-like caged-inducer called cyclofen. Upon UV-light illumination, optical-induced uncaging of Actiflash quickly releases proteins fused to the modified estrogen receptor ligand-binding domains ERT2. This allows them to translocate into the nucleus, activate transcription (using Gal4-UAS system) or induce recombination (using the Cre-lox one).
The protein expression can thus be simply controlled in time and space thanks to UV-light!
產(chǎn)品訂購:
產(chǎn)品名稱 |
貨號(hào) |
規(guī)格 |
光誘導(dǎo)蛋白激活劑 Actiflash |
LJU-CIN-5 |
5mg |
光誘導(dǎo)蛋白激活劑 Actiflash |
LJU-CIN-50 |
50mg |