DESCRIPTION: House Dust Mite (HDM) is a common asthma allergen that more than 85% of asthma patients are sensitive to. Two major house dust mite species, Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farinae (Der f), were found in asthma pathogenesis studies. The mites contain more than 20 types of HDM allergens; group 1 (Der 1) and group 2 (Der 2) allergens dominate overall allergic responses in patients and are the most commonly researched allergens (1-3).
Biotinylated HDM extract from Dermatophagoides pteronyssinus (Der p: Catalog # 3044)
Biotinylated HDM extract from Dermatophagoides farinae (Der f; Catalog # 3045)
Note: Dust mite extract has a unique composition depending on the mite raw materials. The reactivity of this product may differ from batch to batch.
QUANTITY: 0.1 mg protein, lyophilized
APPLICATION: To detect anti-HDM antibodies as well as to study the localization and metabolism of HDM. Chondrex, Inc. recommends pairing biotinylated HDM with a streptavidin conjugated probe (an enzyme or a fluorochrome).
STORAGE TEMPERATURE: -20°C
STABILITY: 2 years
REFERENCES: 1. W. R. Thomas, W. Smith, House-dust-mite allergens. Allergy 53, 821-832 (1998).
2. A. Custovic, S. C. Taggart, H. C. Francis, M. D. Chapman, A. Woodcock, Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 98, 64-72 (1996).
3. A. Jacquet, The role of innate immunity activation in house dust mite allergy. Trends Mol Med 17, 604-611 (2011).